Population pharmacokinetics of caspofungin among extracorporeal membrane oxygenation (ECMO) patients during the postoperative period of lung transplantation(LTx).

Conclusion:ECMO did not have a significant impact on the PK of caspofungin in patients after LTx. Some factors were identified as statistically significant covariates related to the PK of caspofungin ; however, their impact on clinical practice of caspofungin needs to be investigated further in more studies.
PMID: 32816724 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - August 16, 2020 Category: Microbiology Authors: Wang Q, Zhang Z, Liu D, Chen W, Cui G, Li P, Zhang X, Li M, Zhan Q, Wang C Tags: Antimicrob Agents Chemother Source Type: research