Nitric oxide debilitates the neuropathogenic schistosome Trichobilharzia regenti in mice, partly by inhibiting its vital peptidases

Avian schistosomes, the causative agents of human cercarial dermatitis (or swimmer ’s itch), die in mammals but the mechanisms responsible for parasite elimination are unknown. Here we examined the role of reac...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research

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Publication date: Available online 10 October 2020Source: Journal of Genetics and GenomicsAuthor(s): Chengqi Wang, Justin Gibbons, Swamy R. Adapa, Jenna Oberstaller, Xiangyun Liao, Min Zhang, John H. Adams, Rays H.Y. Jiang
Source: Journal of Genetics and Genomics - Category: Genetics & Stem Cells Source Type: research
Authors: Abdeta D, Kebede N, Giday M, Terefe G, Abay SM Abstract Microbial resistance to the few conventional antitrypanosomal drugs, increasing resistance of vectors to insecticides, lack of effective vaccines, and adverse effects of the existing antitrypanosomal drugs justify the urgent need for effective, tolerable, and affordable drugs. We assessed antitrypanosomal effects of the hydromethanolic extract of Echinops kebericho Mesfin roots against Trypanosoma congolense field isolate using in vitro and in vivo techniques. Parasite load, packed cell volume (PCV), body weight, and rectal temperature in Swiss albino...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Conclusion: This study demonstrates that the crude extract of A. hispidum DC, one of the plants used traditionally to treat malaria, inhibits the growth of P. falciparum in vitro and could be a potential source of antimalarial drug. The report has highlighted genotoxic and cytotoxic effects of the selected plant extracts on human leukocytes as well. PMID: 33029160 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
(Nagoya University) Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzymeβ-1,4-glucanase (GH9B3) as an important contributor to both phenomena. Targeting this enzyme may help control plant parasitism in crops.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
SUPPLEMENTS could be used to treat some of your dry skin problems at home this winter. If you have itchy eczema symptoms, you should consider adding these cheap capsules to your daily diet, as they provide an easy treatment for your skin alongside more common eczema creams and moisturisers.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
In this study, we present a new method for the simultaneous detection of CXCR4, mesodermal markers and NCCs markers during chicken embryo developmental stages HH18 –HH25 by combining double whole-mount in situ hybridization (ISH) and immunostaining on floating vibratome sections. The simultaneous detection of CXCR4 and markers for the mesodermal and neural crest cells in multiple labelling allowed us to compare complex gene expression patterns and it could b e easily used for a wide range of gene expression pattern analyses of other chicken embryonic tissues. All steps of the procedure, including the preparation of p...
Source: Histochemistry and Cell Biology - Category: Biomedical Science Source Type: research
Conclusions: The low prevalence of asymptomatic malaria parasite carriage by the children living in the Cape Coast Metropolis suggests that the malaria control interventions in place in CCMA are highly effective and that additional malaria control interventions are required for the KEEA district to reduce the prevalence of asymptomatic malaria parasite carriers. No molecular evidence of P. ovale and P. vivax was identified in the afebrile children sampled from the selected schools. PMID: 33029151 [PubMed]
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
Publication date: Available online 8 October 2020Source: Research in Veterinary ScienceAuthor(s): Ali Raza Jahejo, Wen-xia Tian
Source: Research in Veterinary Science - Category: Veterinary Research Source Type: research
Study seeks to compare microbiomes of our ancestors for clues to modern diseasesResearchers working knee-deep in 14th- and 15th-century latrines have found that bacterial DNA from human excrement can last for centuries and provide clues to how our gut contents have changed significantly since medieval times.Analysis of two cesspits, one in Jerusalem and the other in the Latvian capital, Riga, could help scientists understand if changes to our microbiome – the genetic makeup of the bacteria, virus, fungi, parasites and other microbes living inside us – affect modern-day afflictions.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Science Biology Microbiology Medical research Israel Archaeology Middle East and North Africa World news Source Type: news
Conclusion: The findings of this study can help inform joint patient-physician decision making in managing moderate-to-severe AD. PMID: 33023361 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
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