Successful treatment of metoprolol-induced cardiac arrest with high-dose insulin, lipid emulsion and extracorporeal membrane oxygenation
Beta-adrenergic antagonist toxicity causes cardiovascular collapse often refractory to standard therapy. Alternative therapies include high-dose insulin, lipid emulsion and venoarterial extracorporeal membrane oxygenation (VA-ECMO).CaseA 47-year-old male ingested ten grams of metoprolol tartrate in a suicide attempt. Upon emergency department (ED) presentation, he was comatose, bradycardic and hypotensive. Glucagon (14mg IV) and vasopressor/inotropic support (epinephrine 0.1 mcg/kg/min, dobutamine 10 mcg/kg/min) were administered.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Jeremiah T. Escajeda, Ken D. Katz, Jon C. Rittenberger Tags: Case Report Source Type: research
More News: Alternative and Complementary Therapies | Cardiology | Cardiovascular | Complementary Medicine | Depression | Emergency Medicine | Heart | Insulin | Metoprolol Tartrate | Suicide | Toprol | Toxicology