The Incidence of Invasive Fungal Infections (IFI) in AML Patients Treated with a Hypomethylating Agent

The aim of our study was to selectively analyze newly diagnosed acute myeloid leukemia patients treated with a hypomethylating agent and establish their risk for developing invasive fungal infections (IFI). We stratified patients into concern for IFI (cIFI) versus no concern, and observed that patients of the male gender and those with underlying chronic obstructive pulmonary disease (COPD) are at higher risk for cIFI, which may prompt clinicians to consider anti-mold prophylaxis in this setting.

Source: Clinical Lymphoma, Myeloma and Leukemia - August 20, 2020 Category: Hematology Authors: Michael Ozga, Ying Huang, James S. Blachly, Nicole R. Grieselhuber, Sarah Wall, Karilyn Larkin, Tamanna Haque, Alison R. Walker, Bhavana Bhatnagar, Gregory Behbehani, Sumithira Vasu, Joseph E. Maakaron, Mark Lustberg, Alice S. Mims Tags: Original Study Source Type: research