Analysis of expression profiling data suggests explanation for difficulties in finding biomarkers for nasal polyps.

CONCLUSION: Our findings indicate that the difficulties in finding specific biomarkers for CRSwNP depend on the complex underly-ing mechanisms, which include multiple pathways and regulators, each of which may be subdivided into multiple components such as ligands, soluble and membrane-bound receptors. This suggests that combinations of biomarkers may be needed for CRSwNP diagnostics.
PMID: 32812533 [PubMed - as supplied by publisher]

Source: Rhinology - August 21, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research