Changes in walking velocity and stride parameters with age in children with Charcot-Marie-Tooth disease

Charcot-Marie-Tooth disease (CMT) is a common inherited peripheral neuropathy that affects one in 2500 people [1]. Charcot-Marie-Tooth type 1 (CMT1), the most prevalent subtype, includes patients with dominantly inherited demyelinating neuropathies and CMT type 2 (CMT2) includes patients with dominantly inherited axonal neuropathies. CMT causes functional impairments at the joint level such as distal limb muscle weakness and sensory loss [2], with a typical childhood onset and variable rate of disease progression [3, 4].
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research