Retention of neutralizing antibodies to Japanese encephalitis vaccine in age groups above fifteen years in Korea

Japanese encephalitis (JE), a human viral disease highly prevalent in Asian countries, is transmitted via a zoonotic cycle between vector mosquitoes, such as Culex tritaeniorhynchus, and pigs or water birds as amplifiers (Pearce et al., 2018). The causative pathogen, JE virus (JEV), is a flavivirus of the family Flaviviridae, which includes dengue, Zika, yellow fever, and tick-borne encephalitis viruses (Lazear and Diamond, 2016). JEV has a positive-sense single-stranded RNA genome that may cause asymptomatic infection in some patients and severe neurological manifestations resulting in death in others (Solomon, 2003).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research