Macro-TSH: A Diagnostic Challenge

Conclusion: The patient harboured macro-TSH, which is a rare condition. The complex binding of TSH to other plasma proteins, most often immunoglobulins, results in elevated plasma TSH. However, the biologically active fraction of TSH is normal, reflected by clinical and biochemical euthyroidism.Eur Thyroid J
Source: European Thyroid Journal - Category: Endocrinology Source Type: research