Wearable technology to assess bradykinesia and immobility in patients with severe depression undergoing electroconvulsive therapy: a pilot study - Powell A, Graham D, Portley R, Snowdon J, Hayes MW.

The psychomotor retardation that may be seen in major depression represents an interesting parallel to bradykinesia, a core feature of Parkinson's disease. Psychomotor retardation has been correlated with the severity of depression and is a predictor of re...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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We present the case of a woman with DBS as a treatment for PD, safely treated with ECT for a psychotic depression. Depression severity and motor changes were evaluated on a weekly basis using the Montgomery-Åsberg Depression Rating Scale and the Unified Parkinson's Disease Rating Scale. During the course of ECT, the Montgomery-Åsberg Depression Rating Scale score declined from 34 to 13, and the Unified Parkinson's Disease Rating Scale motor score from 44 to 12 with positive impact on rigidity. Considering the positive impact of ECT on the motor function in our patient, new research should look into ECT as an au...
Source: The Journal of ECT - Category: Psychiatry Tags: Case Reports Source Type: research
Vinutha Ramesh, Ashish Sharma, Veenita Sharma, Aditya SomaniAnnals of Indian Academy of Neurology 2019 22(4):501-503 Parkinson's disease (PD) is known to have associated nonmotor manifestations including psychiatric symptoms such as depression and psychosis. Catatonia has been reported extremely rarely in patients of PD. The case described here is a rare example of catatonia in a patient with PD with psychosis. Treatment with electroconvulsive therapy (ECT) brought improvement in symptoms of both PD and catatonia. ECT appears to be an effective treatment option in patients of PD, especially with psychiatric manifestations.
Source: Annals of Indian Academy of Neurology - Category: Neurology Authors: Source Type: research
Freezing of gait (FOG) is an episodic absence or marked reduction of forward progression of the feet despite the intention to walk [1]. During episodes of freezing, patients feel as if their feet ‘are being glued to the floor’. FOG is common in patients with Parkinson's disease and atypical parkinsonism, and is associated with greater disease severity [2]. Stress, anxiety, a depressive mood and cognitively challenging situations are notorious for provoking or increasing the severity of F OG [3]. Here, we present a patient who clinically presented with a major depressive disorder (MDD) that was accompanied by FO...
Source: Parkinsonism and Related Disorders - Category: Neurology Authors: Tags: Correspondence Source Type: research
Abstract Electroconvulsive therapy (ECT) is the safe application of electricity to the scalp of a patient, using brief-pulse stimulation techniques under general anesthesia and muscle paralysis, inducing a series of generalized epileptic seizures. Principal indications for ECT are major depression (unipolar or bipolar) with a lack of response to medications, intolerance to medications due to side effects or coexisting conditions, the need for a rapid response because of other conditions such as catatonia, psychosis, suicidality, or clinically significant dehydration or malnutrition, mania, and schizophreniform dis...
Source: Journal of Nippon Medical School - Category: Universities & Medical Training Authors: Tags: J Nippon Med Sch Source Type: research
Conclusions: The use of antidepressants, especially SNRIs, was associated with a shorter survival time of sCJD patients. The possible changes in neurotransmitters should be emphasized. Scientifically, this study may provide insights into the mechanism of CJD. Clinically, it may contribute to the early diagnosis of CJD.IntroductionDepression is common in the elderly. Its prevalence rate is as high as 11.19%, and this increases progressively with worsening cognitive impairment (1). The presence of depression is an acknowledged risk factor for dementia (2); it can even double the risk for Alzheimer’s disease (AD) (3, 4)...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Authors: Kaliora SC, Zervas IM, Papadimitriou GN Abstract Electroconvulsive therapy (ECT) is the oldest among the early biological treatments introduced in psychiatry, and the only one still in use. In this paper we attempt a brief presentation of ECT usage over the last 80 years, since it was originally introduced. It is a safe, well-tolerated, and highly effective treatment option for major psychiatric disorders, such as mood disorders and schizophrenia, especially when there is an acute exacerbation of psychotic symptoms or if catatonic symptoms are prominent. ECT has also been used successfully for the treatmen...
Source: Psychiatriki - Category: Psychiatry Tags: Psychiatriki Source Type: research
This article reviews the highly variable evidence supporting the use of ECT in conditions other than depression, such as schizophrenia, bipolar manic states, catatonia, Parkinson disease, and post-traumatic stress disorder.
Source: The Psychiatric Clinics of North America - Category: Psychiatry Authors: Source Type: research
AbstractPurposeTo review the current literature regarding the use and safety of electroconvulsive therapy (ECT) in the elderly population.Recent findingsElectroconvulsive therapy (ECT) is both a safe and effective treatment for geriatric patients with severe psychiatric illness. In an era of often inadequate or poorly tolerated pharmacologic treatments, ECT can provide life-saving treatment for depression, catatonia, movement disorders, and even mood and behavioral dysregulation in dementia syndromes. The Prolonging Remission in Depressed Elderly (PRIDE) study directed by Charles Kellner has provided clear and convincing e...
Source: Current Treatment Options in Psychiatry - Category: Psychiatry Source Type: research
We describe their treatment and review the current literature on the use of ECT among patients with PD. CASE SERIES All six patients in our retrospective chart review received bitemporal modified brief pulse ECT. Prior to ECT, the patients underwent pre-ECT evaluation, which involved hemogram analysis, renal and liver function tests, fasting blood glucose analysis, chest X-ray (posteroanterior view), and serum electrolyte analysis, all of which were within the normal range for all six patients, and none of the patients showed evidence of raised intracranial pressure on fundoscopy examination. All patients provided written ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Review Current Issue Depression Devices ECT Mental Disorders Mood Disorders Movement Disorders Neurology Parkinson's disease Psychiatry Technology Electroconvulsive therapy parkinson’s disease Source Type: research
Amantadine, which was originally developed as an antiviral medication, functions as a dopamine agonist in the central nervous system and consequently is utilized in the treatment of Parkinson disease, drug-induced extrapyramidal reactions, and neuroleptic malignant syndrome. For reasons that are not entirely understood, abrupt changes in amantadine dosage can produce a severe withdrawal syndrome. Existing medical literature describes case reports of amantadine withdrawal leading to delirium, which at times has progressed to neuroleptic malignant syndrome. Amantadine withdrawal may be under-recognized by mental health clini...
Source: Journal of Psychiatric Practice - Category: Psychiatry Tags: Winner of Resident Paper Competition 2016 Source Type: research
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