Accuracy of target delineation by positron emission tomography-based auto-segmentation methods after deformable image registration: A phantom study

Positron emission tomography and computed tomography (PET/CT)-guided radiation treatment planning can improve the accuracy of tumor delineation [1] and reduce inter-observer variability [2]. Moreover, the American Association of Physicists in Medicine Task Group 211 (AAPM TG211) [3] has reported a large variety of PET auto-segmentation (PET-AS) methods to assist with definitive a gross tumor volume (GTV) delineation. Fixed threshold algorithms are based on a standardized uptake value (SUV) and the absolute threshold or the percentage of maximum SUV is used in the target delineation [4,5].
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Tags: Technical note Source Type: research