Growth Retardation of Poorly Transfectable Tumor by Multiple Injections of plasmids Encoding PE40 Based Targeted Toxin Complexed with Poly-ethylenimine.

CONCLUSION: Despite this, three intratumoral injections of a plasmid- polyethylenimine complex resulted in a substantial growth retardation of poorly transfectable D2F2/E2 tumor in mice. There were no significant differences in anti-tumor prop-erties between DNA constructs with telomerase or CAG promoters in vivo. PMID: 32807050 [PubMed - as supplied by publisher]
Source: Current Gene Therapy - Category: Genetics & Stem Cells Authors: Tags: Curr Gene Ther Source Type: research