Beamline B21: high-throughput small-angle X-ray scattering at Diamond Light Source

B21 is a small-angle X-ray scattering (SAXS) beamline with a bending magnet source in the 3   GeV storage ring at the Diamond Light Source Ltd synchrotron in the UK. The beamline utilizes a double multi-layer monochromator and a toroidal focusing optic to deliver 2   ×   1012 photons per second to a 34   ×   40   µ m (FWHM) focal spot at the in-vacuum Eiger   4M (Dectris) detector. A high-performance liquid chromatography system and a liquid-handling robot make it possible to load solution samples into a temperature-controlled in-vacuum sample cell with a high level of automation. Alternatively, a range of viscous or solid materials may be loaded manually using a range of custom sample cells. A default scattering vector range from 0.0026 to 0.34   Å − 1 and low instrument background make B21 convenient for measuring a wide range of biological macromolecules. The beamline has run a full user programme since 2013.

Source: Journal of Synchrotron Radiation - August 17, 2020 Category: Physics Authors: Cowieson, N.P. Edwards-Gayle, C.J.C. Inoue, K. Khunti, N.S. Doutch, J. Williams, E. Daniels, S. Preece, G. Krumpa, N.A. Sutter, J.P. Tully, M.D. Terrill, N.J. Rambo, R.P. Tags: SAXS proteins biological macromolecules solution samples beamlines Source Type: research