Emerging therapeutics for the management of COVID 19.

Emerging therapeutics for the management of COVID 19. Expert Opin Emerg Drugs. 2020 Aug 15;: Authors: Debnath S, Srivastava R, Omri A Abstract INTRODUCTION: The coronavirus-19 (COVID-19) disease pandemic can be characterized as the most critical and changeable hazard to healthcare systems in eras. The high fatality rate associated with coronavirus infection underlines the urgent need for an effective treatment to reduce disease severity and mortality. AREAS COVERED: A detailed search for treatments related to severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) was carried out using PubMed. Components of the virus relevant to the infectious mechanism were identified. We have highlighted all the latest emerging and repurposed drugs that were found to be active against this novel coronavirus and classified these drugs according to their category. Different drug targets are discussed in order to identify new molecules or new combinations as candidates to manage SARS-CoV2/COVID-19 infections. EXPERT OPINION: The development of novel molecules and vaccines has been a challenge during this urgent crisis. Nucleoside analogues and IL-6 receptor antagonists have been identified as the best candidates for treatment of this disease. The results of ongoing clinical trials for many antiviral drugs and vaccines are being awaited eagerly to confirm promising treatments for SARS CoV2. Multi-drug therapy by targeting different ...
Source: Expert Opinion on Emerging Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Emerg Drugs Source Type: research