Viperin protein inhibits the replication of caprine parainfluenza virus 3 (CPIV 3) by interaction with viral N protein.

In conclusion, the bVi and gVi Viperin effectively inhibited CPIV3 replication potentially via the interaction of Viperin with viral N protein. The present results gave more information about antiviral activity of ruminants Viperin and provided foundation for further studies of the interaction of Viperin with CPIV3 and other related viruses.
PMID: 32800881 [PubMed - as supplied by publisher]

Source: Antiviral Research - August 11, 2020 Category: Virology Authors: Li W, Li J, Sun M, Yang L, Mao L, Hao F, Liu M, Zhang W Tags: Antiviral Res Source Type: research