Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock

This randomized clinical trial compares the effect of combination hydrocortisone, ascorbic acid, and thiamine (the HAT or Marik protocol) vs placebo on SOFA score –measured organ injury at 72 hours in patients with septic shock.
Source: JAMA - Category: General Medicine Source Type: research