Reward Responsiveness and Ruminative Styles Interact to Predict Inflammation and Mood Symptomatology.

Reward Responsiveness and Ruminative Styles Interact to Predict Inflammation and Mood Symptomatology.
Behav Ther. 2020 Sep;51(5):829-842
Authors: Moriarity DP, Ng T, Titone MK, Chat IK, Nusslock R, Miller GE, Alloy LB
Abstract
Abnormal reward responsiveness and rumination each are associated with elevated inflammation and mood symptoms. Ruminating on positive and negative affect, or dampening positive affect, may amplify, or buffer, the associations of reward hyper/hyposensitivity with inflammation and mood symptoms. Young adults (N = 109) with high or moderate reward sensitivity completed reward responsiveness and ruminative style measures at the initial visit of a longitudinal study of mood symptoms, a blood draw to assess inflammatory biomarkers, and mood symptom measures at the study visits before and after the day of the blood draw. The interaction between high reward responsiveness and rumination on positive affect was associated with higher levels of an inflammatory composite measure and hypomanic symptoms. The interaction between lower reward responsiveness and high dampening of positive affect was associated with higher levels of the inflammatory composite measure and depressive symptoms. Lower reward responsiveness also interacted with low rumination on positive affect to predict increases in depressive symptoms and higher levels of the inflammatory composite. Thus, levels of reward responsiveness and ruminative response st...

Source: Behavior Therapy - August 18, 2020 Category: Psychiatry & Psychology Authors: Moriarity DP, Ng T, Titone MK, Chat IK, Nusslock R, Miller GE, Alloy LB Tags: Behav Ther Source Type: research