Prevalence of white matter hyperintensities is not elevated in a large sample of adolescents and young adults with bipolar disorder.

CONCLUSION: In contrast to the study hypothesis, the prevalence of white matter hyperintensities was not higher in adolescents with bipolar disorder than controls. The large sample size and good matching for age and sex bolster the reliability of this negative finding. Future studies are warranted to evaluate the prevalence, incidence, and predictors of white matter hyperintensities in early-onset bipolar disorder prospectively.
PMID: 32785453 [PubMed - as supplied by publisher]

Source: Revista Brasileira de Psiquiatria - August 6, 2020 Category: Psychiatry Authors: Mehrhof SZ, Popel N, Mio M, Lu W, Heyn CC, Fiksenbaum LM, MacIntosh BJ, Goldstein BI Tags: Braz J Psychiatry Source Type: research