Garcinoic acid prevents {beta}-amyloid (A{beta}) deposition in the mouse brain [Lipids]

In conclusion, GA holds potential for preventing Aβ oligomerization and deposition in the brain. The mechanistic aspects of GA's properties appear to be distinct from those of other vitamin E metabolites and of genistein.

Source: Journal of Biological Chemistry - August 13, 2020 Category: Chemistry Authors: Rita Marinelli, Pierangelo Torquato, Desiree Bartolini, Cristina Mas–Bargues, Guido Bellezza, Antimo Gioiello, Consuelo Borras, Antonella De Luca, Francesca Fallarino, Bartolomeo Sebastiani, Sridhar Mani, Angelo Sidoni, Jose Vina, Manuela Leri, Moni Tags: Neurobiology Source Type: research