Former Johnson & Johnson exec joins CorneaGen board

CorneaGen announced Thursday that Tom Frinzi, formerly worldwide president of Johnson&Johnson Vision, joined its board of directors. Seattle-based CorneaGen focuses on developing technologies to cure corneal blindness by 2040 and provides donor tissues for cornea transplants. Frinzi, with more than 35 years of experience in ophthalmology, will lead CorneaGen’s board as executive chair, replacing William Link, who will remai n on the board. “Tom’s deep experience in bringing ophthalmology…
Source: Health Care:Pharmaceuticals headlines - Category: Pharmaceuticals Authors: Source Type: news

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Conclusion: The remarkable protective effects of IL-10-BM-MSCs support further developing them into an effective interventional modality against corneal allograft rejection. IL-10-BM-MSCs promote corneal allograft survival mainly through upregulating a novel lncRNA expression in graft-infiltrating CD68+ macrophages. LncRNA, for the first time, is integrated into an IL-10-BM-MSC-driven immunomodulatory axis against the immune rejection to corneal allograft.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
A corneal transplant can cure some forms of blindness and visual impairment. The United States bans men from donating if they have had gay sex in the past five years; Canada has a 12-month restriction.
Source: WebMD Health - Category: Consumer Health News Source Type: news
TUESDAY, Sept. 29, 2020 -- U.S. and Canadian restrictions on cornea donations from gay and bisexual men prevent thousands of vision-restoring transplants and need to be changed, researchers say. A corneal transplant can cure some forms of blindness...
Source: - Daily MedNews - Category: General Medicine Source Type: news
Conclusions: The prevalence of MSVI and blindness from corneal disease in Asia is approximately 0.4%, with a nearly 20-fold difference in the national prevalence across the region. The indications for keratoplasty, reflective of the causes of corneal dysfunction, also vary, more so according to the gross national income than to geographic location, and only a few Asian countries have rates of corneal transplantation above international means.
Source: Cornea - Category: Opthalmology Tags: Review Source Type: research
CONCLUSION: With the aid of a supported hospital partnership modern minimally invasive corneal transplantation techniques can be successfully transferred to the eye hospital of a developing country and in return surgical skills can be taught to surgeons from Germany who are in training. Therefore, an efficient hospital partnership is the basis for a mutual exchange and is not purely one-way traffic. PMID: 32725542 [PubMed - as supplied by publisher]
Source: Der Ophthalmologe - Category: Opthalmology Authors: Tags: Ophthalmologe Source Type: research
Conclusion: Although Fusarium keratitis remains a rare complication of CL wear, we found a significant increase of cases in the Netherlands. The course of infection may be severe and fungal diagnosis was often delayed. Antifungal treatment strategies varied widely and the treatment failure rate was high, requiring transplantation or even enucleation. Our study underscores the need for systematic surveillance of fungal keratitis and a consensus management protocol.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Authors: Jemberu YT, Woldie YA, Mulugeta W, Shiferaw Alemu D, Bantie GM Abstract Background: For so long, corneal diseases have been known as one of the leading causes to blindness in the global. This blindness might be due to failure to accept the corneal transplantation. Therefore, this study aimed to determine the prevalence and the root challenges for corneal transplantation acceptance at the University of Gondar tertiary eye care and training center, Ethiopia. Methods: An institution-based cross-sectional study was conducted among patients who had an indication for corneal transplantation at the University...
Source: Journal of Ophthalmology - Category: Opthalmology Tags: J Ophthalmol Source Type: research
Three researchers at the  Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have received awards totaling more than $18 million from the California Institute for Regenerative Medicine, the state’s stem cell agency. The recipients areDr. Sophie Deng, professor of ophthalmology at the UCLA Stein Eye Institute;  Yvonne Chen, a UCLA associate professor of microbiology, immunology and molecular genetics; andDr. Caroline Kuo, a UCLA assistant clinical professor of pediatrics. The awards were announced at a CIRM meeting today.Deng ’s four-year, $10.3 million award ...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
We report a case series of four patients with PKDL, across three districts of Bihar state, who developed eye complications during treatment. They presented with acute scleritis and corneal infiltration with or without corneal ulceration. One patient solely with corneal infiltration recovered completely. The three others with corneal ulceration healed with corneal opacificity. One patient with bilateral eye involvement underwent corneal transplantation to prevent blindness. All adverse events were graded as certain using the World Health Organization-Uppsala Monitoring Centre causality assessment scale. There is need to cou...
Source: Tropical Doctor - Category: Tropical Medicine Authors: Tags: Trop Doct Source Type: research
CorneaGen focuses on innovating technologies to cure corneal blindness by 2040 and provides donor tissues for cornea transplants.
Source: Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
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