Molecular Mechanism of a Specific NLRP3 Inhibitor to Alleviate Seizure Severity Induced by Pentylenetetrazole.

CONCLUSION: These findings indicate that CY-09 may represent an important treatment agent for epilepsy and other NLRP3 inflammasome-associated diseases.
PMID: 32778044 [PubMed - as supplied by publisher]

Source: Epilepsy Curr - August 9, 2020 Category: Neurology Authors: Shen K, Jiang W, Zhang C, Cai L, Wang Q, Yu H, Tang Z, Gu Z, Chen B Tags: Curr Mol Pharmacol Source Type: research