A Family Cluster of Coronavirus Disease (COVID-19) Infection with Different Clinical Manifestations.

This report describes the epidemiological, clinical, radiological, laboratory findings, and different clinical manifestation of a family cluster of COVID-19 case in Indonesia. COVID-19 was transmitted from asymptomatic person in the incubation period. PMID: 32778630 [PubMed - in process]
Source: Acta medica Indonesiana - Category: Internal Medicine Tags: Acta Med Indones Source Type: research

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Authors: Assadiasl S, Fatahi Y, Zavvar M, Nicknam MH Abstract The newly emerged severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has recently caused pandemic Coronavirus Disease-2019 (COVID-19). Considering the serious medical, economic and social consequences of this pandemic and the lack of definite medication and vaccine it is necessary to describe natural immune responses to the SARS-CoV-2 in order to exploit them for treating the patients and monitoring the general population. Moreover, detecting the most immunogenic antigens of the virus is fundamental for designing effective vaccines. Ant...
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
CONCLUSION Forty-five percent of trauma patients are asymptomatic at the time of SARS-CoV-2 diagnosis. Respiratory symptoms, as well as verbal screening (recent fevers, shortness of breath, cough, international travel, and close contact with known SARS-CoV-2 carriers), are inaccurate in the trauma population. These findings demonstrate the need for comprehensive rapid testing of all trauma patients upon presentation to the trauma bay. LEVEL OF EVIDENCE Diagnostic tests or criteria, level III, Therapeutic/care management, level IV.
Source: Journal of Trauma and Acute Care Surgery - Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research
With an ever-climbing tally of COVID-19 infections, deaths, and calculations about how quickly the virus is spreading, the numbers can start to lose meaning. But one million is a resonant milestone. According to the Johns Hopkins Coronavirus Resource Center, the world has now lost one million lives to the new coronavirus. It’s easy to draw analogies—one million people dying of COVID-19 would be the equivalent of just over the entire population of a country like Djibouti, or just under the populace of Cyprus. Perhaps more sobering would be to think of that number less as an entity and more in terms of the precio...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 News overnight UnitedWeRise20Disaster Source Type: news
ConclusionsNPS of dementia during COVID-19 appear to arise from social restrictions occurring as a consequence of the pandemic. Implementation of caregiver support and the presence of skilled nursing home staff are required to restore social interaction and adjust technological support to the patients’ needs.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
The emerging coronavirus disease (COVID-19) caused by SARS-CoV-2 has led to social and economic disruption globally. It is urgently needed to understand the structure and function of the viral proteins for understanding of the viral infection and pathogenesis and development of prophylaxis and treatment strategies. Coronavirus non-structural protein 1 (nsp1) is a notable virulence factor with versatile roles in virus-host interactions and exhibits unique characteristics on sequence, structure, and function mode. However, the roles and characteristics of SARS-CoV-2 nsp1 are currently unclear. Here, we analyze the nsp1 of SA...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This study provides useful insights for the identification of potential non-pathogenic (to humans) surrogates to understand inactivation kinetics and their use in experimental validation of UV-C disinfection systems. This approach can be used to narrow the number of surrogates used in testing UV-C inactivation of other human and animal ssRNA viral pathogens for experimental validation that can save cost, labor and time.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
ObjectivesIn March 2020, the World Health Organization declared that an infectious respiratory disease caused by a new severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2, causing coronavirus disease 2019 (COVID-19)] became a pandemic. In our study, we have analyzed a large publicly available dataset, the Genome Aggregation Database (gnomAD), as well as a cohort of 37 Russian patients with COVID-19 to assess the influence of different classes of genetic variants in the angiotensin-converting enzyme-2 (ACE2) gene on the susceptibility to COVID-19 and the severity of disease outcome.ResultsWe demonstrate that the Eur...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Abstract The rapid and abrupt transmission pattern of the SARS-CoV-2 unleashed the current COVID-19 pandemic, as recognized by the World Health Organization in March 2020. Considering the high risk of transmission of the virus in dental environments and the specificities in clinical practice, COVID-19 posed immediate challenges for dental care and education. Due to the need to establish infection prevention and control guidance in dental health settings to enable a safe clinical practice, this review aims to list the challenges and perspectives in managing dental care in services and schools. This review employed materials...
Source: Journal of Applied Oral Science - Category: Dentistry Source Type: research
MONDAY, Sept. 28, 2020 -- Fewer than 10 percent of the U.S. adult population formed antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first wave of the pandemic, according to a study published online Sept. 25...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Coronavirus disease 2019 (COVID-19) is a viral illness, caused by the novel severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). It is currently affecting millions of people worldwide and is associated with coagulopathy, both in the venous and arterial systems. The proposed mechanism being excessive inflammation, platelet activation, endothelial dysfunction, and stasis. As an ongoing pandemic declared by WHO in March 2020, health systems worldwide are experiencing significant challenges with COVID-19-related complications. It has been noticed that patients with COVID-19 are at greater risk of thrombosis.Case Rep N...
Source: Case Reports in Neurology - Category: Neurology Source Type: research
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