Loss of Laminin α3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma.

CONCLUSIONS: These data provide evidence that loss of the laminin α3 chain in cSCC has an effect on both the epithelial and immune components of cSCC resulting in an aggressive tumour microenvironment.
PMID: 32767748 [PubMed - as supplied by publisher]

Source: The British Journal of Dermatology - August 6, 2020 Category: Dermatology Authors: Caley MP, Martins VL, Moore K, Lashari M, Nissinen L, Kähäri VM, Alexander S, Jones E, Harwood CA, Jones J, Donaldson M, Marshall JF, O'Toole EA Tags: Br J Dermatol Source Type: research