A systematic review of the effects of probiotic administration in inflammatory arthritis.
CONCLUSION: This review indicates there may be differential benefits to combined formulations of Bifidobacteriales and Lactobacillales compared to purely Lactobacillales formulations, with respect to reducing pain, lowering CRP and improving quality of life. It also suggests variable benefits associated with the type of inflammatory arthritis. Relatively less benefit for lowering CRP was attributed to individuals with SpA compared to individuals with RA. Generalisability of results to clinical practice is limited by the dominant demographic of older individuals with established disease beyond the 'therapeutic window of intervention'. Small but statistically significant benefits require confirmation in clinical studies with greater consideration to potentially confounding factors of age, gender, diet and individual microbial signature.
PMID: 32771911 [PubMed - as supplied by publisher]
Source: Complementary Therapies in Clinical Practice - Category: Complementary Medicine Authors: Lowe JR, Briggs AM, Whittle S, Stephenson MD Tags: Complement Ther Clin Pract Source Type: research
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