Longitudinal Strain Reflects Ventriculoarterial Coupling Rather Than Mere Contractility in Rat Models of Hemodynamic Overload –Induced Heart Failure

Longitudinal strain (LS) is a sensitive marker of systolic function. Recent findings suggest that both myocardial contractility and loading conditions determine LS. The aim of this study was to investigate whether LS reflects the connection of cardiac contractility to afterload (termed ventriculoarterial coupling [VAC]) rather than mere contractility in rat models of hemodynamic overload –induced heart failure (HF).

Source: Journal of the American Society of Echocardiography - August 6, 2020 Category: Cardiology Authors: Mih ály Ruppert, Bálint Károly Lakatos, Szilveszter Braun, Márton Tokodi, Christian Karime, Attila Oláh, Alex Ali Sayour, István Hizoh, Bálint András Barta, Béla Merkely, Attila Kovács, Tamás Radovits Source Type: research