Electronic health records to facilitate continuous detection of familial hypercholesterolemia

Familial hypercholesterolemia (FH) is an inherited disorder associated with increased risk of coronary heart disease as a result of high LDL-cholesterol (LDL-C). The clinical diagnosis can be made with the Dutch Lipid Clinic Network criteria (DLCN criteria). FH is an underdiagnosed disorder, possibly due to false negative LDL-C interpretation during lipid lowering therapy (LLT). We hypothesized that automated health record-based integration of data can provide a signal to facilitate identification of FH patients.

Source: Atherosclerosis - August 7, 2020 Category: Cardiology Authors: Shari Pepplinkhuizen, Shirin Ibrahim, Rutger Vink, Bas Groot, Erik S.G. Stroes, Willem A. Bax, Jan H. Cornel Source Type: research