Black bronchoscopy in a patient with pulmonary malignant melanoma: A case report

Black pigmentation of the airways (black bronchoscopy) can be caused by many etiologies. We herein reported a case of black bronchoscopy for pulmonary malignant melanoma. A 47 ‐year‐old Japanese man was referred to our hospital with a one‐week history of chest discomfort. Chest computed tomography (CT) revealed a mass in the right upper lobe suspected to be primary lung cancer. A biopsy of the mass using endobronchial ultrasonography (EBUS) with guide sheath (GS) wa s performed, and a black‐colored mass was observed which occluded almost all of the right B2b bronchus. Immunohistochemistry of lung specimens was compatible with a diagnosis of malignant melanoma which was confirmed to be BRAF wild ‐type. Furthermore, positron emission tomography (PET) and contrast‐enhanced magnetic resonance imaging (MRI) of the head revealed multiple metastatic lesions in the brain, liver, and bones. The patient was referred to another hospital for specific treatment. After that, the patient's melanoma w as confirmed to have the BRAF wild‐type gene and PD‐L1 expression was 80%. Then, combined therapy of nivolumab plus ipilimumab was subsequently administered.
Source: Thoracic Cancer - Category: Cancer & Oncology Authors: Tags: IMAGING IN THORACIC CANCER Source Type: research