Looping the (R) Loop in DSB Repair via RNA Methylation

In this issue of Molecular Cell, Zhang et  al. (2020) reveal that ATM triggers RNA methylation of DNA-RNA hybrids formed at double-strand breaks (DSBs) to modulate repair, adding a new layer of complexity to RNA’s role in the DNA damage response.

Source: Molecular Cell - August 5, 2020 Category: Cytology Authors: Bel én Gómez-González, Andrés Aguilera Tags: Preview Source Type: research