Functional variants in the promoter region of macrophage migration inhibitory factor rs755622 gene (MIF G173C) among patients with heart failure: Association with echocardiographic indices and disease severity

Heart failure (HF) is a multifaceted, etiology varied clinical syndrome leading to high levels of morbidity and mortality worldwide. The prevalence of HF continues to rise following 65 years, affecting almost 1 in 100 people. Atherosclerosis and concurrent ischemic heart disease are the most prevalent cause of HF in the developed world. Hypertension (which conducting to degenerated hypertrophy that can lead to cardiomyopathy and HF), dilated non-ischemic cardiomyopathy and genetic factors include other causes.
Source: Heart and Lung - Category: Intensive Care Authors: Source Type: research