Sperm morphology: what implications on the assisted reproductive outcomes?

AbstractObjectiveTo evaluate the impact of sperm morphology (SM) on laboratory and pregnancy outcomes in conventional intracytoplasmic sperm injection (c ‐ICSI) cycles, using the egg donation model to minimize female confounding variables.Materials and methodsWe retrospectively collected data of oocyte donation cycles from October 2016 to February 2020. Median seminal parameters, total (1 ‐2‐3PN) fertilization rate (FR), 2PN FR, cleavage rate (CR), implantation rate (IR), pregnancy rate (PR), miscarriage rate (MR) and live birth rate (LBR) were collected. The study population was divided into three groups: Group 1 with SM 6%.Results741 fresh ICSI cycles and 4507 warmed oocytes were included. Male age was 46.0 (31.0 ‐72.0) years and recipients’ age was 44.0 (29.0‐54.0) years. Normal SM was 5.0% (1.0‐15.0%). Male age was negatively correlated with normal SM (p=0.002; Rho −0.113). Oocyte survival rate was 83.3% (16.7‐100.0%). Total FR was 75.0% (11.1‐100.0%), 2PN FR was 66.7% (11.1‐100.0%) %, CR was 100% (0.0‐100%).Comparing samples with SM> 6% and those with SM6% (p6%, compared to other groups (p=0.02 andp
Source: Andrology - Category: Urology & Nephrology Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Authors: Reissier S, Cattoir V Abstract INTRODUCTION: Streptogramins (pristinamycin and quinupristin-dalfopristin) can be interesting options for the treatment of infections due to Gram-positive cocci, especially multidrug-resistant isolates. AREAS COVERED: This review provides an updated overview on structural and activity characteristics, mechanisms of action and resistance, pharmacokinetic/pharmacodynamic and clinical use of streptogramins. EXPERT OPINION: The streptogramin antibiotics act by inhibition of the bacterial protein synthesis. They are composed of two chemically distinct compounds, namely typ...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Publication date: 15 February 2021Source: Journal of Hazardous Materials, Volume 404, Part BAuthor(s): Jinsoo Lee, Seong-Jin Choi, Ji-Seong Jeong, Sang Yun Kim, Sang-Hyub Lee, Mi Jin Yang, Seung-Jin Lee, Young-Jun Shin, Kyuhong Lee, Eun Ju Jeong, Sang-Yoon Nam, Wook-Joon Yu
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
Conclusions: This review results revealed a low utilization of postnatal care service. Antenatal care service utilization has a positive effect on postnatal care service utilization. Policymakers and programmers better considered more antenatal care service use as one strategy of enhancing the utilization of postnatal care service. PMID: 33029402 [PubMed - in process]
Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
Authors: Debelew GT Abstract Despite several efforts globally, the problem of perinatal mortality remained an unsolved agenda. As a result, it continued to be an essential part of the third sustainable development goals to end preventable child deaths by 2030. With a rate of 33 per 1000 births, Ethiopia has the highest level of perinatal mortality in the world. Thus, determining the magnitude and identifying the determinants are very crucial for evidence-based interventions. A community-based longitudinal study was conducted in Southwest Ethiopia among 3474 pregnant women to estimate the magnitude of perinatal mort...
Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
This study was aimed at assessing the magnitude of induced abortion and associated factors among students in Hawassa University, southern region, Ethiopia, 2019. Methods: An institutional-based cross-sectional study was conducted among a total of 422 students selected on the bases of a probability simple random sampling method. A pretested structured questionnaire was used to collect data. Analysis was made with SPSS 20. Descriptive summary and inferential statistics (binary logistic regression) were used with a 95% CI and P value of less than 5% as a level of significance. Findings were presented in tables, figure, an...
Source: Journal of Pregnancy - Category: OBGYN Tags: J Pregnancy Source Type: research
AbstractBackgroundNowadays, serodiscordant couples (SDCs) with human immunodeficiency virus (HIV) or hepatitis C virus (HCV) ‐infected men have the chance to conceive safely, giving birth with a minimum risk of cross‐infection.ObjectiveTo assess the impact of male HIV and HCV infection on the assisted reproductive technologies (ART) outcomes in SDCs, with HIV or HCV seropositive men and negative partners.Materials and methodsOf 153 couples: 24 in Group 1 (HIV ‐seropositive men), 60 in Group 2 (HCV‐seropositive men) and 69 in Group 3 (controls). Sperm‐washing procedure was performed using a three‐step system. Fr...
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research
Contributors : Aarthi Narayanan ; Aura Garrison ; Bibha Dahal ; Brett Beitzel ; Catherine E Campbell ; Chelsea Pinkham ; Connie Schmaljohn ; Cynthia L de la Fuente ; Gustavo Palacios ; Kylene Kehn-Hall ; Michael Linquidst ; Nicole BracciSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensRift Valley fever virus (RVFV) causes major outbreaks among livestock, characterized by “abortion storms” in which spontaneous abortion occurs in almost 100% of pregnant ruminants. Humans can also become infected with mild symptoms that can progress to more severe symptoms, such as hepatitis, ...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
The mosquito-borne Rift Valley fever virus has been linked to miscarriage in humans. A study of 130 pregnant Sudanese women with fever showed that the risk of miscarriage was seven times greater if the woman was infected with Rift Valley fever virus.
Source: ScienceDaily Headlines - Category: Science Source Type: news
This study is the first to show an association between infection with Rift Valley fever virus and miscarriage in pregnant women. Further studies are warranted to investigate the possible mechanisms. Our findings have implications for implementation of preventive measures, and evidence-based information to the public in endemic countries should be strongly recommended during Rift Valley fever outbreaks. Funding Schlumberger Faculty for the Future, CRDF Global (31141), the Swedish International Development Cooperation Agency, the County Council of Västerbotten, and the Faculty of Medicine, Umeå University.
Source: The Lancet Global Health - Category: Global & Universal Source Type: research
Rift Valley Fever, a mosquito-borne disease, can devastate a sheep herd causing 90 percent mortality in lambs and 100 percent abortion rates in pregnant ewes. Current vaccines either don't provide long-term immunity or cause spontaneous abortions in pregnant ewes. Now researchers are developing a new vaccine that is proving to be both safe and effective.
Source: ScienceDaily Headlines - Category: Science Source Type: news
More News: Coccidioidomycosis (Valley Fever) | ICSI (Intracytoplasmic Sperm Injection) | Laboratory Medicine | Miscarriage | Pregnancy | Study | Urology & Nephrology