Concerns regarding the safety of azithromycin in pregnancy - relevance for women with cystic fibrosis

Chronic oral azithromycin therapy improves clinical outcomes in people with cystic fibrosis (CF) [1], and is recommended for treatment of CF lung disease [2]. Azithromycin is categorized as pregnancy class B; no evidence of impaired fertility or fetal harm was observed in mice and rats at maternally toxic doses [3]. However, no adequate/well-controlled studies are likely to be performed in pregnant women.

Source: Journal of Cystic Fibrosis - August 11, 2020 Category: Respiratory Medicine Authors: Jennifer L. Taylor-Cousar, Raksha Jain, Tracy M. Kazmerski, Moira L. Aitken, Natalie E. West, Alexandra Wilson, Peter G. Middleton, Edward F. Nash Source Type: research