Effect of vessel wall segmentation on volumetric and radiomic parameters of coronary plaques with adverse characteristics

Information on the reproducibility of quantitative coronary plaque features with regards to differences in segmentation are scarce. In 100 coronary plaques with adverse imaging characteristics, we found that expert readers have good reproducibility for total, noncalcified and calcified plaque volumes (ICC: 0.84, 0.83 and 0.96), however for low-attenuation noncalcified plaque reproducibility was fair (ICC: 0.65). Radiomic features had good reproducibility (ICC>0.80) in 88.6% of first-order, 62.0% of gray level co-occurrence matrix, 75.8% of gray level run length matrix and 19.8% of geometrical parameters. Differences in segmentation may significantly change feature values therefore scientific results should be interpreted with caution.
Source: Journal of Cardiovascular Computed Tomography - Category: Radiology Authors: Tags: Research paper Source Type: research