Glyoxal and Methylglyoxal as E-cigarette Vapor Ingredients-Induced Pro-Inflammatory Cytokine and Mucins Expression in Human Nasal Epithelial Cells.

CONCLUSIONS: GO and MGO induced pro-inflammatory cytokines and MUC5AC/5B expression via ERK1/2, p38 MAPK, and NF-κB in human nasal epithelial cells. These results suggested that GO and MGO may be involved in mucus hypersecretion-related airway diseases.
PMID: 32746708 [PubMed - as supplied by publisher]

Source: American Journal of Rhinology and Allergy - August 2, 2020 Category: ENT & OMF Authors: Kwak S, Choi YS, Na HG, Bae CH, Song SY, Kim YD Tags: Am J Rhinol Allergy Source Type: research