Modelling, docking and simulation analysis of Bisphenol A interaction with laccase from Trichoderma.

Modelling, docking and simulation analysis of Bisphenol A interaction with laccase from Trichoderma. Bioinformation. 2020;16(4):323-331 Authors: Ramakrishnan SG, Sivaramakrishnan M, Chenthamara D, Kothandan R, Krishnaswami S, Subramaniam S Abstract Fungal laccases are widely known for the degradation of recalcitrant xenobiotic compounds. Hence, it is of interest to study the interaction between laccase from Trichoderma laccase and Endocrine-Disrupting Chemical (EDC) named Bisphenol A. The molecular docking analysis of laccase from Trichoderma laccase with 23 xenobiotics and bisphenol A was completed. We show Bisphenol having optimal binding features (Glide score of -5.44 and the Glide energy -37.65 kcal/mol) with laccase from Trichoderma laccase. PMID: 32773992 [PubMed]
Source: Bioinformation - Category: Bioinformatics Authors: Tags: Bioinformation Source Type: research