Clinicopathological features and differential diagnosis of chondrogenic tumours

Chondrogenic or cartilaginous tumours represent the most common bone tumours and can be diagnostically challenging especially on scarce biopsy material. As morphologically they may overlap, correlation between radiological and pathological findings and discussion in a multidisciplinary tumour board is mandatory for a final diagnosis. The aim of this review is to discuss clinical and pathological features that are important in the differential diagnosis of benign (chondromesenchymal hamartoma of chest wall, osteochondroma, enchondroma, periosteal chondroma) and intermediate (synovial chondromatosis, central or secondary peripheral atypical cartilaginous tumour) or malignant cartilaginous tumours (central or secondary peripheral chondrosarcoma grades 1 –3, periosteal chondrosarcoma, dedifferentiated chondrosarcoma, clear cell chondrosarcoma and mesenchymal chondrosarcoma).
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Mini-symposium: Bone pathology Source Type: research