Use of Remdesivir for Pregnant Patients with Severe Novel 2019 Coronavirus Disease
[Nation] The focus on containing the spread of coronavirus has hit crucial mother-to-child health care services, including family planning and immunisation, research has shown.
ConclusionsIn this case series of 67 test ‐positive women with clinical presentation ranging from asymptomatic to manifest COVID‐19 disease few women presented with severe COVID‐19 illness, a majority had a vaginal birth at term with a healthy neonate that were test‐negative for SARS‐CoV‐2.
AbstractThe novel coronavirus outbreak induces many concerns about the management of pregnancy, as well as rheumatic and musculoskeletal diseases. The very rapid spread of the infection throughout all inhabited continents leads to a fast-growing number of infected with SARS-CoV-2 and requires answers and special recommendations to the most vulnerable group of people: pregnant woman and patients on immunomodulatory or immunosuppressive treatment. A systematic literature search was performed in Embase, MEDLINE, and Scopus database for studies describing COVID-19 infection in pregnant women diagnosed with rheumatic and muscul...
AbstractRepurposing of antirheumatic drugs has garnered global attention. The aim of this article is to overview available evidence on the use of widely used antirheumatic drugs hydroxychloroquine, methotrexate and colchicine for additional indications. Hydroxychloroquine has endothelial stabilizing and anti-thrombotic effects. Its use has been explored as an adjunctive therapy in refractory thrombosis in antiphospholipid syndrome. It may also prevent recurrent pregnancy losses in the absence of antiphospholipid antibodies. Hydroxychloroquine favourably modulates atherogenic lipid and glycaemic profiles. Methotrexate has b...
Shiltz J, Sutton M, West N, Schaffner W, Talbot HK, George A, Spencer M, Ellington S, Galang RR, Gilboa SM, Tong VT, Piasecki A, Brammer L, Fry AM, Hall AJ, Wortham JM, Kim L, Garg S, COVID-NET Surveillance Team Abstract Pregnant women might be at increased risk for severe coronavirus disease 2019 (COVID-19) (1,2). The COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) (3) collects data on hospitalized pregnant women with laboratory-confirmed SARS-CoV-2, the virus that causes COVID-19; to date, such data have been limited. During March 1-August 22, 2020, approximately one in four hospitalized wo...
This report describes that the prevalences of prepregnancy obesity and gestational diabetes were higher among pregnant women hospitalized for COVID-19-related illness than among those admitted for pregnancy-related treatment or procedures and found to have COVID-19.
This report describes clinical characteristics and birth outcomes of hospitalized U.S. pregnant women with COVID-19 during March 1-August 22, 2020.
AbstractOn April 7, 2020 Mehreen Zaigham and Ola Andersson published a systematic review of maternal and perinatal outcomes in 108 pregnancies with Covid ‐19 concluding that careful monitoring of such pregnancies and is warranted.1 We would like to emphasise the need to assess objectively the impact of the novel Severe Acute Respiratory Coronavirus Type 2 (SARS ‐CoV‐2) causing Covid‐19 disease on pregnancy and perinatal outcomes by conducting epidemiological studies among pregnant women.
CONCLUSIONS: The medical facility experienced a major decline in all aspects of the routine obstetrics activities during the time of the pandemic. The higher rate of operative vaginal deliveries among nulliparous may be associated with the pandemic effect on the rate of high-risk patients. PMID: 32954690 [PubMed - in process]
ConclusionBased on the result of this study, it is necessary to pay more attention to the mental health of pregnant women during a pandemic. In addition, it is recommended to provide a virtual training group to reduce anxiety caused by coronavirus and pregnancy concerns, as well as emphasizing the feeling of enjoying happiness caused by pregnancy experience during a pandemic.