Long-term prognostic value of longitudinal measurements of blood neurofilament levels

Conclusions NfLlong had a higher prognostic value than single NfL assessments on long-term outcomes in RRMS. Combining it with clinical and MRI measures increased sensitivity and specificity to predict long-term disease outcomes. Classification of evidence This study provides Class I evidence that NfLlong was more strongly associated with long-term outcomes than single NfL assessments in patients with RRMS.

http://nn.neurology.org/cgi/content/short/7/5/e856?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - August 11, 2020 Category: Neurology Authors: Häring, D. A., Kropshofer, H., Kappos, L., Cohen, J. A., Shah, A., Meinert, R., Leppert, D., Tomic, D., Kuhle, J. Tags: Multiple sclerosis Article Source Type: research