Regional microglial activation in the substantia nigra is linked with fatigue in MS

Conclusion Substantia nigra microglial activation is linked to fatigue in MS. Microglial activation across key brain regions may represent a unifying mechanism for MSAF, and further evaluation of neuroimmunologic basis of MSAF is warranted.

http://nn.neurology.org/cgi/content/short/7/5/e854?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - August 6, 2020 Category: Neurology Authors: Singhal, T., Cicero, S., Pan, H., Carter, K., Dubey, S., Chu, R., Glanz, B., Hurwitz, S., Tauhid, S., Park, M.-A., Kijewski, M., Stern, E., Bakshi, R., Silbersweig, D., Weiner, H. L. Tags: PET, Multiple sclerosis Article Source Type: research