Interleukin-26, preferentially produced by TH17 lymphocytes, regulates CNS barrier function

Conclusions
Our study demonstrates that although IL-26 is preferentially expressed by TH17 lymphocytes, it promotes BBB integrity in vitro and in vivo and is protective in chronic EAE, highlighting the functional diversity of cytokines produced by TH17 lymphocytes.

Source: Neurology Neuroimmunology and Neuroinflammation - August 10, 2020 Category: Neurology Authors: Broux, B., Zandee, S., Gowing, E., Charabati, M., Lecuyer, M.-A., Tastet, O., Hachehouche, L., Bourbonniere, L., Ouimet, J.-P., Lemaitre, F., Larouche, S., Cayrol, R., Bouthillier, A., Moumdjian, R., Lahav, B., Poirier, J., Duquette, P., Arbour, N., Peele Tags: All Immunology, Autoimmune diseases, Multiple sclerosis Article Source Type: research