Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide

In this study, we demonstrate that brachyury expression can impair aggressive glioma features associated with treatment resistance. Finally, we provide the first evidence that brachyury can be a potential therapeutic target in GBM patients who do not respond to conventional chemotherapeutic drugs.
Source: Neurotherapeutics - Category: Neurology Source Type: research