Need for Additional Trials of Vitamin C for Sepsis —Reply

In Reply A total of 14 studies (8 randomized trials and 6 observational studies) have already evaluated the effects of high-dose vitamin C, thiamine, and steroids in more than 2000 patients with sepsis in 10 different countries, and the overall results have been disappointing. In addition, 12 other trials are now completed according to ClinicalTrials.gov. Thus, a large amount of new information on this combination treatment will soon be reported.
Source: JAMA - Category: General Medicine Source Type: research