WT1 expression in peripheral blood at diagnosis and during the course of early consolidation treatment correlates with survival in patients with intermediate and poor risk acute myeloid leukaemia

Dynamics of WT1 expression during the course of chemotherapy was tested in 106 cases of intermediate and high-risk acute myeloid leukaemia in peripheral blood. High WT1 expression after 2 cycles of chemotherapy was a significant prognostic factor for OS and EFS in the whole cohort, as well as in patients treated without allogeneic stem cell transplantation (HSCT).

Source: Clinical Lymphoma, Myeloma and Leukemia - August 9, 2020 Category: Hematology Authors: Cyril Šálek, Jan Vydra, Ela Cerovská, Šárka Šestáková, Šárka Ransdorfová, Veronika Válková, Petr Cetkovský, Hana Remešová Tags: Original Study Source Type: research