Up-regulation of MMP-2 by histone H3K9 β -hydroxybutyrylation to antagonize glomerulosclerosis in diabetic rat

ConclusionBHB treatments could up-regulate MMP-2 generation via causing elevated H3K9bhb in its promoter to antagonize glomerulosclerosis in the diabetic rats.
Source: Acta Diabetologica - Category: Endocrinology Source Type: research