Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu ‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases

ConclusionsCYP1A2, 2C19 and UGT1As play an important role in isobavachin metabolism. Isobavachin demonstrated broad ‐spectrum inhibition of CYPs and UGTs.

Source: Journal of Pharmacy and Pharmacology - August 3, 2020 Category: Drugs & Pharmacology Authors: Han Xing, Jing Yang, Kaidi Ren, Zifei Qin, Peile Wang, Xiaojian Zhang, Zhihong Yao, Frank J. Gonzalez, Xinsheng Yao Tags: Research Paper Source Type: research