Familial aggregation of atopic dermatitis and co-aggregation of allergic diseases in affected families in Taiwan

Atopic dermatitis (AD) is a chronic and relapsing dermatitis, mainly presenting in infants and children. AD affects 6.7 % of the total population in Taiwan. The prevalence in females is 7.5 %, which is higher than males (5.9 %) [1]. The recent findings of gene-gene and gene-environment interaction hypothesized the three phases of the natural history of AD. The genetically determined skin-barrier dysfunction and the effect of environmental factors result in the initial phase of atopic dermatitis.
Source: Journal of Dermatological Science - Category: Dermatology Authors: Source Type: research