Genomic alterations in chronic lymphocytic leukemia and their correlation with clinico-hematological parameters and disease progression.

Conclusion: Genetic abnormalities are commonly (65%) observed in CLL patients. Del(13q), which is associated with DLEU2 and DLEU1/RB1 gene deletion, was the most common. Compared with other abnormalities, del(11q) and del(17p) patients presented with cytopenia and higher Binet stage, while those with del(13q14) had a longer time to first treatment. PMID: 32747613 [PubMed - as supplied by publisher]
Source: Blood Research - Category: Hematology Tags: Blood Res Source Type: research