Quantifying the Size of the Pterygium Head by Evaluating the Fibrous Area or the Vascularized Area

Conclusions: With both methods, reproducibility of the size of the pterygium head was high. Significant differences were shown between the two methods in quantification of the width and length but not in the surface area. Such methods can be used to standardize the evaluation of pterygia in clinical research and clinical trials.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research

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ConclusionOur findings demonstrated that when intact, the biological stress systems adaptively support organisms during stress by focusing attention towards specific stimuli that are relevant to the threat. Dysregulations of the stress systems result in important system specific consequences on threat evaluation, such that suppression of either stress system alone resulted in reduced threat assessment for contextually relevant threatening stimuli, whereas when both systems were suppressed, individuals appear indiscriminately attentive to all potential threats in the environment, resulting in increased threat processing of ...
Source: Psychopharmacology - Category: Psychiatry Source Type: research
Contributors : Junren Sia ; Jun Fang ; Song LiSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTraumatic injury often results in muscle loss and impairment, which is worsened under aged and diseased conditions. Activation of resident stem cells or transplantation of myogenic stem cells can promote muscle regeneration. However, major challenges remain in harvesting sufficient autologous myogenic stem cells and expanding such cells efficiently for muscle regeneration therapies. Here, we identified a chemical cocktail that selectively induced a robust expansion of myogenic stem cells from...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Contributors : Junren Sia ; Song LiSeries Type : Expression profiling by arrayOrganism : Mus musculusTraumatic injury often results in muscle loss and impairment, which is worsened under aged and diseased conditions. Activation of resident stem cells or transplantation of myogenic stem cells can promote muscle regeneration. However, major challenges remain in harvesting sufficient autologous myogenic stem cells and expanding such cells efficiently for muscle regeneration therapies. Here, we identified a chemical cocktail that selectively induced a robust expansion of myogenic stem cells from readily-obtainable dermal cells...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
ConclusionPET with [11C]mHED but not [18F]LMI1195 provides information on NET function in the mouse heart. [11C]mHED PET is dose-independent in the mouse myocardium at
Source: EJNMMI Research - Category: Radiology Source Type: research
α1-adrenergic receptors are G-Protein Coupled Receptors that are involved in neurotransmission and regulate the sympathetic nervous system through binding and activating the neurotransmitter, norepinephrine, and the neurohormone, epinephrine. There are three α1-adrenergic receptor subtypes (α1A, α1B, α1D) that are known to play various roles in neurotransmission and cognition. They are related to two other adrenergic receptor families that also bind norepinephrine and epinephrine, the β- and α2-, each with three subtypes (β1, β2, β3, α2A, α2B, α2C). ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion: little research on the theme, recently developed and published, mostly in European countries, was found. This shows the need for a greater number of studies to strengthen the scientific evidence.RESUMEN Objetivo: identificar y analizar la evidencia disponible sobre los valores de referencia para la ganancia del reflejo vest íbulo ocular, obtenido a través del test de impulso cefálico asistido por video. Método: se realizó una revisión integrativa guiada por protocolo PRISMA en las bases de datos Proquest, Ebsco, Pubmed, ScienceDirect, Cochrane Library, LILACS y Scielo d...
Source: Revista CEFAC - Category: Speech-Language Pathology Source Type: research
Dear Investor, Please find attached a press release from our partner Sarepta Therapeutics:https://investorrelations.sarepta.com/news-releases/news-release-details/sarepta-therapeutics-reports-sustained-functional-improvement Do not hesitate to contact us for any further questions. With best regards,
Source: Roche Investor Update - Category: Pharmaceuticals Source Type: news
Dysferlinopathies are a form of limb girdle muscular dystrophy (LGMDR2 dysferlin-related) caused by gene mutations resulting in deficiency of the membrane-associated protein dysferlin. Symptoms manifest post growth in a muscle specific manner, although the pathomechanism is not well understood. One feature is many lipid droplets present in slow-twitch dysferlin-deficient myofibres of humans and mice, and more recently we identified an increased capacity for fatty acid esterification to triglycerides in the predominantly slow-twitch soleus of young adult (3 months) dysferlin-deficient BLAJ, compared with wild type (WT) mice.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
This study also aimed to understand the nutrition priorities for this patient population and their families.
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
Advancement in the management of Duchenne muscular dystrophy (DMD) has resulted in earlier diagnosis of this condition thus allowing for early intervention. Younger patients than before are recruited into disease modifying and other interventional trials. Therefore, the need to understand the course of the disease, achievement and decline of physical function, in a younger cohort of patients has been recognized. Previous research has identified that while typically developing children reach their peak function (as measured by Northstar Ambulatory Assessment, NSAA) at 4 years, DMD boys show a progressive increase in NSAA sc...
Source: Neuromuscular Disorders - Category: Neurology Authors: Source Type: research
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