A healthy gut for a healthy brain: preclinical, clinical and regulatory as-pects.

A healthy gut for a healthy brain: preclinical, clinical and regulatory as-pects. Curr Neuropharmacol. 2020 Jul 29;: Authors: Petrella C, Farioli-Vecchioli S, Cisale GY, Strimpakos G, Borg JJ, Ceccanti M, Fiore M, Monteleone G, Nisticò R Abstract A large body of research has shown the presence of a complex pathway of communications between the gut and the brain. It is now recognized that, through this pathway, the microbiota can influence brain homeostasis and plasticity under normal and pathological conditions. This review aims at providing an overview of preclinical and clinical pieces of evidence supporting the possible role of gutbrain axis modulation in physiological aging, in a neurodevelopmental disorder, the autism spectrum disorders and in a substance abuse disorder, the alcohol addiction. Since the normalization of gut flora can prevent changes in the behavior, we postulate that the gut-brain axis might represent a possible target for pharmacological and dietary strategies aimed at improving not only intestinal but also mental health. The present review also reports some regulatory considerations regarding the use of probiotics, illustrating the most debated issues about the possibility of considering probiotics not only as a food supplement but also as a "full" medicinal product. PMID: 32744976 [PubMed - as supplied by publisher]
Source: Current Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Neuropharmacol Source Type: research

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Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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Source: Frontiers in Neurology - Category: Neurology Source Type: research
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Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction Personal Recovery Source Type: blogs
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Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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Source: Psych Central - Category: Psychiatry Authors: Tags: Addictions Autism / Asperger's Book Reviews Children and Teens Disorders General Genetics Psychology addiction and genetics books on genomics genetically influenced disorders genetically influenced problems in childhood genomics an Source Type: news
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