Pan-Genome-Scale Network Reconstruction: Harnessing Phylogenomics Increases the Quantity and Quality of Metabolic Models.

CONCLUSIONS: Curating ortholog and reaction databases at higher taxonomic-levels increases the quantity and quality of strain GENREs than the common practice of using model organism GENREs as templates. This pan-GENRE framework provides the ability to scale high-quality GENREs to more branches in the tree of life. This article is protected by copyright. All rights reserved. PMID: 32744423 [PubMed - as supplied by publisher]
Source: Biotechnology Journal - Category: Biotechnology Authors: Tags: Biotechnol J Source Type: research