Early-life exposure to air pollution and childhood allergic diseases: An update on the link and its implications.

Early-life exposure to air pollution and childhood allergic diseases: An update on the link and its implications. Expert Rev Clin Immunol. 2020 Aug 01;: Authors: Lu C, Norbäck D, Li Y, Deng Q Abstract INTRODUCTION: Although mounting evidence has linked environmental factors with childhood allergies, some specific key issues still remain unclear: what is the main environmental factor? what is the critical timing window? And whether these contribute to the development of disease? AREAS COVERED: This selective review summarizes recent epidemiological studies into the association between early-life exposure to indoor and outdoor air pollution, and childhood allergic diseases. A literature search was conducted in the PubMed and Web of Science for peer-reviewed articles published until April 2020 that assessed the relationship between early-life exposure to air pollution and childhood allergic diseases. Exposure to the traffic-related air pollutant, NO2, exposure during pregnancy and early postnatal periods is found to be associated with childhood allergies, and exposure during different trimesters causes different allergic diseases. However, exposure to classical air pollutants (PM10 and SO2) during developing countries cannot be overlooked, and also contribute to childhood allergy. In addition, early-life exposure to indoor renovation, including new furniture, and mould/dampness significantly increases the risk of childhood alle...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research