USTekinumab in Fistulising Perianal Crohn's Disease (USTAP)

Condition:   Crohn's Disease Interventions:   Drug: Ustekinumab;   Drug: Placebo Sponsors:   Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives;   Janssen, LP Not yet recruiting
Source: - Category: Research Source Type: clinical trials

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This report describes 2 patients with UC in whom postoperative pain following oral and maxillofacial surgery was managed by intravenous patient-controlled analgesia with pentazocine. Apart from the development of acute dystonia in 1 case that was likely due to the use of droperidol for prevention of postoperative nausea and vomiting, postoperative pain was well controlled by pentazocine in both patients without any complications or UC exacerbations. PMID: 32992337 [PubMed - in process]
Source: Anesthesia Progress - Category: Anesthesiology Tags: Anesth Prog Source Type: research
This article aims to provide a concise overview of the anatomy, physiology, and molecular biology of sacroiliitis to aid clinicians in the assessment and management of sacroiliitis. For this narrative review, we evaluated articles in English published before August 2019 in PubMed. Then, we selected articles related to the painful manifestations of the sacroiliac joint. From the retrieved articles, we found that chronic sacroiliitis may be caused by various forms of spondyloarthritis, such as ankylosing spondyloarthritis. Sacroiliitis can also be associated with inflammatory bowel disease, Crohn's disease, gout, tuberculosi...
Source: Korean Journal of Pain - Category: Anesthesiology Tags: Korean J Pain Source Type: research
Publication date: Available online 29 September 2020Source: Computers in Human BehaviorAuthor(s): Junzhang Zhao, Hongxing Han, Bu Zhong, Wenjing Xie, Ying Chen, Min Zhi
Source: Computers in Human Behavior - Category: Information Technology Source Type: research
Differentiating between ulcerative colitis (UC), Crohn ’s disease (CD) and intestinal tuberculosis (ITB) using endoscopy is challenging. We aimed to realize automatic differential diagnosis among these diseases...
Source: BMC Medical Informatics and Decision Making - Category: Information Technology Authors: Tags: Research article Source Type: research
Endoscopic remission is a recognized therapeutic endpoint in inflammatory bowel disease (IBD; Crohn ’s disease (CD), ulcerative colitis (UC)). The impact of persistent histologic activity on long-term outcomes is less clear and limited by small studies.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
In conclusion, gut inflammation associated with chronic colitis does not mediate a further increase in the cellular entry of SARS-CoV-2. PMID: 32975064 [PubMed - in process]
Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
PMID: 32974786 [PubMed - in process]
Source: Der Chirurg - Category: Surgery Authors: Tags: Chirurg Source Type: research
We report a case of a 62-year-old female patient with acute exacerbation of ulcerative colitis associated with infiltrating purple-erythematous skin plaques, which were partly vesicular, and oral ulcerative stomatitis. Biopsy was consistent with bullous Sweet's syndrome. Treatment with betamethasone sodium phosphate, starting at 5.5 mg, followed by gradual dose tapering for 12 weeks, resulted in improvement of the ulcerative colitis and disappearance of the cutaneous lesions. Bullous Sweet's syndrome most commonly occurs in the setting of hematologic malignancies, suggesting that physicians should perform long-term screeni...
Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica - Category: Dermatology Tags: Acta Dermatovenerol Alp Pannonica Adriat Source Type: research
FRIDAY, Sept. 25, 2020 -- Fertility is lower in women with inflammatory bowel disease (IBD), according to a study published online Sept. 19 in the Journal of Crohn's and Colitis. Emma Druvefors, from County Hospital Ryhov in J önköping, Sweden, and...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
ConclusionThe association of eosinophilic pneumonia with Ustekinumab, a drug used in the treatment of psoriasis and other autoimmune diseases, is rare and there is a paucity of literature regarding this association. PMID: 32962463 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
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